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The effects of Meisoindigo on inflammasome proteins. (A) Western blot analysis showing that Mei treatment reduces the expression of NLRP3 inflammasome associated proteins, including NLRP3, ASC, CL-caspase-1 and IL-18, in the ischemic cortical tissue after 3 days of reperfusion. (B–E) Quantitative analysis of the protein levels of NLRP3, ASC, CL-caspase-1, and IL-18 in the ischemic cortical tissue. Mean ± SD, n = 5; aP < 0.05 vs. sham; bP < 0.05 vs. vehicle; cP < 0.05 vs. Mei.
