Table 1. Clinical scenarios for summative usability testing.

Scenario	Correct special processing requests
A 15-year-old girl with menorrhagia has a history of hives that appeared with a transfusion of pRBCs that she received two months ago. The transfusion was completed with administration of Benadryl, and there were no signs of anaphylaxis (GI distress, hypotension and respiratory distress). She is presenting with symptomatic anemia and needs another transfusion of pRBCs.	None
You are caring for a premature infant born at 27 weeks of gestation (birth weight 1,100 g) who is now at 35 weeks adjusted gestational age (weight 2,500 g). This patient was recently diagnosed with necrotizing enterocolitis, and you would like to treat this patient with a blood transfusion.	Irradiated
An 18 year-old with acute myeloid leukemia has received multiple platelet transfusions for platelet counts of less than 10,000/μL (<10 k/μL). Two days ago, his 1-hour postplatelet transfusion count remained <10 k/µL. Transfusion medicine was consulted and confirmed that the patient has antibody mediated platelet refractoriness. He needs another platelet transfusion today for a platelet count of 6 k/µL.	Irradiated HLA-matched
A 12-year-old with hemoglobin SC disease presents to the Emergency Department for management of splenic sequestration. You would like to transfuse the patient an aliquot of 5 mL/kg pRBCs. Historically, this patient has no autoantibodies or alloantibodies.	Phenotypically similar
A 7-month-old boy diagnosed with DiGeorge's syndrome and severe combined immunodeficiency presents in aplastic crisis and needs a transfusion of pRBCs.	Irradiated

Abbreviations: GI: gastrointestinal; HLA: human leukocyte antigen; pRBCs: packed red blood cells.