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. 2019 Dec 19;10:2979. doi: 10.3389/fimmu.2019.02979

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Copyright © 2019 Ishisono, Mano, Yabe and Kitaguchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of pectin feeding on dextran sulfate sodium (DSS)-induced colitis in mice. (A) Experimental design and time-course of treatment. Changes in (B) body weight and (C) food intake, and (D) disease activity index (DAI) score for the 8 days following DSS administration. Colon length (E,F) representative histological section images and score 8 days following DSS administration. Levels of colonic (G) interleukin (IL)-1β, (H) IL-6, and (I) tumor necrosis factor (TNF)-α 8 days following DSS administration. Scale bars: 100 μm. Values are presented as means ± standard error of the mean (n = 10–12). Values not sharing a common letter (a or b) were significantly different (P < 0.05). ^*P < 0.05; ^**P < 0.01.

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