Table 7.
Study | Location | Intervention of interest | Indication | Comparator therapy | Mean total cost (2019 USD) | ICER (2019 USD) | Conclusion | Comments |
---|---|---|---|---|---|---|---|---|
Huntington, et al. [160] | USA | Routine follow-up including biannual CT | DLBCL patients in first remission | Routine follow-up with no imaging | Total per-patient costs: biannual CT, $45,723; no imaging, $42,084 | $181,000/QALY | Not cost-effective | Conclusions were robust across one-way and probabilistic sensitivity analyses |
Routine follow-up including biannual PET/CT | DLBCL patients in first remission | Routine follow-up with no imaging | Total per-patient costs: biannual PET/CT, $46,778; no imaging, $42,084 | $186,000/QALY | Not cost-effective | Conclusions were robust across one-way and probabilistic sensitivity analyses |
Abbreviations: CT, computed tomography; DLBCL, diffuse large B-cell lymphoma; ICER, incremental cost-effectiveness ratio; PET, positron-emission tomography; QALY, quality-adjusted life year; USD, US dollars