. Author manuscript; available in PMC: 2020 Jan 10.

Published in final edited form as: Eur J Clin Nutr. 2019 Jun 26;74(1):87–96. doi: 10.1038/s41430-019-0460-7

Table 2.

HR and 95% CI for All-Cause Mortality by γ-Tocopherol Quartiles

γ-Tocopherol Quartiles (μg/mL)	Median (μg/mL)	Participants (N)	Deaths (N)	HR (95% CI)^a	P_trend^a
			Men
Model 1^b
Q1 (0.27–1.17)	0.96	973	198	1.00
Q2 (1.17–1.63)	1.39	974	211	1.18 (0.97–1.43)
Q3 (1.63–2.28)	1.92	968	223	1.25 (1.02–1.52)
Q4 (2.28–11.02)	2.86	972	237	1.43 (1.17–1.74)	0.0005
Model 2^c
Q1 (0.27–1.17)	0.96	971	192	1.00
Q2 (1.17–1.63)	1.39	968	209	1.12 (0.92–1.38)
Q3 (1.63–2.28)	1.92	960	220	1.23 (1.00–1.50)
Q4 (2.28–11.02)	2.86	963	235	1.15 (0.93–1.41)	0.23
Model 3^d
Q1 (0.27–1.17)	0.96	973	198	1.00
Q2 (1.17–1.63)	1.39	974	211	1.16 (0.96–1.42)
Q3 (1.63–2.28)	1.92	968	223	1.23 (1.01–1.49)
Q4 (2.28–11.02)	2.86	972	237	1.34 (1.09–1.63)	0.006
			Women
Model 1^b
Q1 (0–1.17)	0.97	1113	136	1.00
Q2 (1.17–1.66)	1.40	1112	139	1.06 (0.84–1.35)
Q3 (1.66–2.39)	1.98	1114	138	1.11 (0.87–1.41)
Q4 (2.39–13.97)	2.98	1113	181	1.58 (1.25–2.00)	<0.0001
Model 2^c
Q1 (0–1.17)	0.97	1110	136	1.00
Q2 (1.17–1.66)	1.40	1106	139	1.03 (0.81–1.32)
Q3 (1.66–2.39)	1.98	1101	137	1.04 (0.82–1.34)
Q4 (2.39–13.97)	2.98	1110	179	1.38 (1.08–1.75)	0.005
Model 3^d
Q1 (0–1.17)	0.97	1113	136	1.00
Q2 (1.17–1.66)	1.40	1112	139	1.07 (0.85–1.37)
Q3 (1.66–2.39)	1.98	1114	138	1.07 (0.84–1.36)
Q4 (2.39–13.97)	2.98	1113	181	1.45 (1.14–1.83)	0.001

HR, 95% CI and P values were estimated by Cox proportional hazards models.

Model 1: Adjusted by Cox regression for age at blood draw, race/ethnicity (as a strata variable) and serum cholesterol levels.

Model 2: Adjusted by Cox regression for variables in Model 1, and further adjusted for history of cancer, cardiovascular diseases, diabetes, and hypertension and smoking related variables.

Model 3: Adjusted by Cox regression for variables in Model 1, and further adjusted for C-reactive protein (log-transformed).