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. 2019 Dec 17;2(4):239–251. doi: 10.1002/ame2.12093

Figure 3.

Figure 3

Regulatory role of lncRNAs in Parkinson's disease. A variety of lncRNAs are associated with different mechanisms like protein misfolding and aggregation, dysregulated protein degradation, mitochondrial dysfunction, oxidative stress, autophagy, apoptosis, neuroinflammation, and other pathomechanisms (including dopamine metabolism, neurotrophic factors, and PD‐related genes) that ultimately account for the pathological manifestations and clinical symptoms of PD