Table 1.
Clinical characteristics based on timing of ICD placement from last hospitalization for HF.
| Overall (N = 81,180) | Patients Admitted for HF (N = 11563) | HF Admission ≤3 months† (N = 6,252) | HF Admission >3 months† (N = 63,365) | |
|---|---|---|---|---|
| Demographics* | ||||
| Age - Mean (SD) | 73 (8) | 73 (9) | 74 (8) | 73 (8) |
| Sex: Female | 28 | 29 | 32 | 27 |
| Race | ||||
| White non-Hispanic | 83 | 75 | 78 | 85 |
| Black non-Hispanic | 11 | 16 | 15 | 9 |
| Hispanic | 4 | 6 | 5 | 4 |
| Other | 2 | 2 | 2 | 2 |
| Clinical Characteristics | ||||
| NICM | 38 | 40 | 39 | 38 |
| LVEF, Mean (SD) | 26 (6) | 23 (7) | 24 (7) | 26 (6) |
| NYHA Class | ||||
| I | 2 | 1 | 1 | 3 |
| II | 31 | 15 | 21 | 36 |
| III | 63 | 74 | 73 | 60 |
| IV | 3 | 11 | 5 | 2 |
| Atrial fibrillation/flutter | 40 | 48 | 44 | 38 |
| Cerebrovascular Disease | 17 | 20 | 19 | 17 |
| Currently on Dialysis | 3 | 4 | 4 | 3 |
| Diabetes | 42 | 49 | 49 | 41 |
| Chronic Lung Disease | 25 | 34 | 31 | 22 |
| QRS Duration, Median (25th-75th) | 127 (103-154) | 130 (104-154) | 130 (104-156) | 126 (102-154) |
| Left Bundle Branch Block | 35 | 34 | 36 | 35 |
| BUN, Mean (SD) | 26 (14) | 32 (16) | 31 (15) | 25 (12) |
| Sodium, Mean (SD) | 139 (3) | 138 (4) | 138 (4) | 139 (3) |
| Hemoglobin, Mean (SD) | 13.0 (1.8) | 12.1 (1.9) | 12.5 (1.8) | 13.2 (1.7) |
| Procedure | ||||
| Implanted Device Type | ||||
| Single Chamber | 19 | 16 | 17 | 19 |
| Dual Chamber | 27 | 25 | 22 | 27 |
| CRT-D | 55 | 59 | 60 | 53 |
| Discharge Medications | ||||
| ACEI | 58 | 55 | 55 | 59 |
| ARB | 21 | 17 | 20 | 22 |
| Beta-Blockers | 91 | 89 | 90 | 91 |
| Hydralazine | 5 | 10 | 9 | 4 |
| Long Acting Nitroglycerin | 13 | 17 | 17 | 12 |
| Digoxin | 18 | 24 | 22 | 17 |
| Diuretics | 71 | 81 | 86 | 68 |
| Aspirin | 71 | 70 | 70 | 72 |
| Statins | 70 | 66 | 67 | 71 |
| Non-Statin | 11 | 8 | 10 | 12 |
| Antiarrhythmic Agents | 13 | 18 | 16 | 11 |
| Channel Blockers | 9 | 8 | 9 | 9 |
| Warfarin | 30 | 34 | 32 | 29 |
| Thienopyridines | 24 | 22 | 24 | 24 |
*
all numbers are calculated using complete cases within each variable
†
3 months defined as 90 days
Abbreviations: ICD = implantable cardioverter-defibrillation; HF = heart failure; SD = standard deviation; NICM = nonischemic cardiomyopathy; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; CRT-D = cardiac resynchronization therapy-defibrillator; ACEI = angiotensin converting-enzyme inhibitor; angiotensin receptor blocker.