Fig. 5.

Embryograms of femaleB. pahangishow that CBR417 and CBR490 affect late stages of developing mf.Both CBR417 and CBR490 (40 mg/kg QD for 7 days) significantly reduced the number of later-staged mf. Female worms recovered from jirds treated with CBR417 also had significantly more degenerated embryos in their ovaries. Embryonic stages (oocytes, embryos, pre-mf, stretched mf and degenerated embryos) per female adult worm were removed from jirds infected with B. pahangi and counted from the ovaries and uteri of individual worms. Results are shown as mean relative frequencies of embryonic stages ± SEM