Table 4.

CBR417 reduced the number of B. pahangi microfilariae that were released from female worms recovered from jirds at necropsy. Female worms were recovered from jirds and cultured overnight to assess the number of mf released by each worm. 89% of female worms from animals treated with CBR417 did not shed mf (8 of 9 female worms).

Treatment	# females shedding mf	# females not shedding mf	% females not shedding mf
Vehicle	7	9	56%
CBR417 QD 40 mpk x 7d	1	8	89%
CBR490 QD 40 mpk x 7d	6	6	50%
CBR490 QD 20 mpk x 7d	13	4	24%
CBR490 QD 10 mpk x 7d	8	4	33%