Effects of knockdown of LSR, TRIC, ASPP2, PAR3, and YAP in Sawano cells.
(A) Immunocytochemical staining for LSR (green), TRIC (green), ASPP2
(green), PAR3 (green), and pYAP (green) with acetylated tubulin (red) in
Sawano cells treated with 100 ng/ml Taxol after transfection with siRNAs
of LSR, TRIC, ASPP2, PAR3, and pYAP. Bars: 5 μm. (B) Immunocytochemical
staining for LSR, TRIC, ASPP2, PAR3, and pYAP with γ-tubulin in Sawano
cells treated with 100 ng/ml Taxol after transfection with siRNAs of
LSR, TRIC, ASPP2, PAR3, and pYAP. Bars: 5 μm. (C) Bar graph of cell
cycle assay in Sawano cells transfected with siRNA of LSR. (D) Bar graph
of cell cycle assay in Sawano cells transfected with siRNA of ASPP2.
Abbreviations: LSR, lipolysis-stimulated lipoprotein receptor; TRIC,
tricellulin; ASPP2, apoptosis-stimulating of p53 protein 2; pYAP,
phosphorylated yes-associated protein; OCLN, occludin; CLDN-7,
claudin-7; ZO-1, zonula occludens-1; siRNA, small interfering RNA.