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. 2019 Dec 23;13(2):287–294. doi: 10.1016/j.tranon.2019.09.011

Figure 1.

Figure 1

PBK was highly expressed in GBM cells. (A) Kinome-wide screening of 538 human kinase-encoding genes in chemoradiation resistant GBM cells compared with nontumor (Murat's dataset [17]). (B) Kinome-wide screening of 538 human kinase-encoding genes in GBM cells compared with nontumor (Mao's dataset [16]). (C) Venn diagram identified PBK as one of the most differentially expressed kinase-encoding genes in these two databases. (D) PBK was highly enriched in GBM cell lines compared with astrocyte according to RT-qPCR analysis. (E and F) The Western blotting analysis showed the elevated expression levels of PBK in GBM cell lines compared with normal human astrocytes (NHA). β-Actin served as the control. **P < 0.01.