Table 4.
Univariate Analysis of DFS and OS Considering the Combination of cNHERF1 Expression and TILs Levels in the Overall Group and TNBC Patients.
| Characteristics | N. Pts | DFS |
OS |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N. Events | 5-yr % DFS | p | HR (95% CI) | p | N. Events | 5-yr % OS | p | HR (95% CI) | P | ||
| Overall Patients | |||||||||||
| Other | 277 | 58 | 84 | 1.00 | 23 | 93 | 1.00 | ||||
| cNHERF1−/TILs+ | 49 | 5 | 93 | 0.049 | 0.41 (0.16–1.03) | 0.057 | 3 | 93 | 0.483 | 0.65 (0.20–2.17) | 0.487 |
| TNBC Patients | |||||||||||
| Other | 95 | 26 | 76 | 1.00 | 10 | 89 | 1.00 | ||||
| cNHERF1−/TILs+ |
13 |
0 |
100 |
0.031 |
Not estimable |
– |
0 |
100 |
0.209 |
Not estimable |
|
| Overall Patients | |||||||||||
| Other | 214 | 42 | 85 | 1.00 | 15 | 94 | 1.00 | ||||
| cNHERF1−/TILs− | 112 | 21 | 86 | 0.861 | 1.05 (0.62–1.77) | 0.860 | 11 | 90 | 0.276 | 1.54 (0.70–3.35) | 0.280 |
| TNBC Patients | |||||||||||
| Other | 68 | 13 | 84 | 1.00 | 2 | 97 | 1.00 | ||||
| cNHERF1−/TILs− | 40 | 13 | 72 | 0.057 | 2.08 (0.96–4.49) | 0.063 | 8 | 78 | 0.002 | 8.15 (1.73–38.47) | 0.008 |
Bold indicates P < 0.05.