. Author manuscript; available in PMC: 2020 Dec 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 Sep 11;144(6):1524–1533. doi: 10.1016/j.jaci.2019.08.033

Table VI:

Multivariable Models Stratified by Self-Reported Race for Exacerbations in Trial Cohorts with Genetic Ancestry Data.

Significant exacerbation Predictors	Blacks, with ancestry data available (n=161)^a		Whites, with ancestry data available (n=489)^a
	RR (95% CI)	P-value	RR (95%CI)	P-value
Exacerbation history		0.83		0.19
≥2 vs 0	1.5 (0.37–6.34)	0.56	1.4 (0.48–3.83)	0.57
1 vs 0	1.2 (0.35–4.33)	0.75	1.7 (0.96–3.13)	0.07
Sex (Females versus Males)	0.9 (0.31–2.52)	0.82	0.7 (0.41–1.28)	0.27
% pred FEV1, per 14% increase	1.1 (0.59–1.89)	0.86	0.8 (0.64–1.07)	0.16
%AA (median cutpoint)	3.4 (1.15–9.81)	0.027	1.5 (0.92, 2.51)	0.10

Relative rates (RR) for continuous variables expressed per change by one standard deviation. Models include median percentage African genetic ancestry (AA) which varied between races due to marked differences in distribution of Native American, European, and African ancestries. Models also include protocol, age, sex, FEV1, race, and exacerbation history.

Poisson regression.