Table 3.
Unadjusted Weight Outcomes From Baseline Overall and by Cardiometabolic Risk Groups
| All Participants | Baseline | 3 Months | 6 Months | 12 Months | 18 Months | 24 Months |
|---|---|---|---|---|---|---|
| All participants, No. | 3156 | 2851 | 2129 | 2334 | 2013 | 1736 |
| Weight, mean ± SD, kg | 101.33 ± 23.84 | 98.10 ± 23.10 | 97.47 ± 23.47 | 97.79 ± 23.46 | 97.87 ± 23.31 | 98.38 ± 23.32 |
| Time to follow-up, mean ± SD, mo | 2.60 ± 0.46 | 5.57 ± 0.69 | 11.76 ± 1.17 | 17.92 ± 1.27 | 24.02 ± 1.29 | |
| Absolute weight change from baseline, mean (95% CI), kg | −3.45 (−3.60 to −3.30) | −4.05 (−4.33 to −3.78) | −3.31 (−3.61 to −3.00) | −2.66 (−2.97 to −2.34) | −2.41 (−2.80 to −2.02) | |
| Percent weight change from baseline, mean (95% CI) | −3.39 (−3.52 to −3.25) | −3.92 (−4.17 to −3.67) | −3.20 (−3.48 to −2.92) | −2.57 (−2.87 −2.27) | −2.27 (−2.61 to −1.92) | |
| ≥5% weight loss, No. (%) | 833 (29.22) | 769 (36.12) | 712 (30.51) | 574 (28.51) | 505 (29.09) | |
| ≥7% weight loss, No. (%) | 453 (15.89) | 516 (24.24) | 516 (22.11) | 401 (19.92) | 365 (21.03) | |
| High risk for T2D, No. | 1493 | 1381 | 1038 | 1106 | 940 | 824 |
| Weight, mean ± SD, kg | 103.22 ± 24.33 | 99.22 ± 23.40 | 97.73 ± 23.71 | 98.26 ± 23.81 | 98.24 ± 23.53 | 99.49 ± 23.86 |
| Time to follow-up, mean ± SD, mo | 2.61 ±7.52 | 5.58 ± 0.68 | 11.76 ± 1.17 | 17.93 ± 1.29 | 24.00 ± 1.33 | |
| Absolute weight change from baseline, mean (95% CI), kg | −3.81 (−4.04 to −3.60) | −4.65 (−5.08 to −4.23) | −3.79 (−4.24 to −3.34) | −2.89 (−3.34 to −2.45) | −2.85 (−3.46 to −2.25) | |
| Percent weight change from baseline, mean (95% CI) | −3.69 (−3.89 to −3.50) | −4.50 (−4.86 to −4.13) | −3.69 (−4.10 to −3.28) | −2.86 (−3.27 to −2.44) | −2.68 (−3.20 to −2.17) | |
| ≥5% weight loss, No. (%) | 445 (32.22) | 421 (40.56) | 375 (33.91) | 280 (29.79) | 260 (31.55) | |
| ≥7% weight loss, No. (%) | 252 (18.25) | 293 (28.23) | 278 (25.14) | 196 (20.85) | 187 (22.69) | |
| Overweight/obese, No. | 858 | 748 | 511 | 575 | 490 | 410 |
| Weight, mean ± SD, kg | 94.40 ± 20.55 | 91.50 ± 19.91 | 91.14 ± 20.77 | 91.20 ± 21.01 | 91.47 ± 20.67 | 90.60 ± 19.44 |
| Time to follow-up, mean ± SD, mo | 2.58 ± 0.47 | 5.55 ± 0.68 | 11.76 ± 1.24 | 18.01 ±1.40 | 24.06 ± 1.34 | |
| Absolute weight change from baseline, mean (95% CI), kg | −3.23 (−3.53 to −2.94) | −3.68 (−4.24 to −3.12) | −2.91 (−3.47 to −2.33) | −2.26 (−2.88 to −1.64) | −1.76 (−2.45 to −1.07) | |
| Percent weight change from baseline, mean (95% CI) | −3.42 (−3.71 to −3.13) | −3.88 (−4.41 to −3.35) | −3.04 (−3.61 to −2.47) | −2.42 (−3.05 to −1.78) | −1.88 (−2.59 to −1.17) | |
| ≥5% weight loss, No. (%) | 234 (31.28) | 191 (37.38) | 161 (28.00) | 129 (26.33) | 121 (29.51) | |
| ≥7% weight loss, No. (%) | 126 (16.84) | 128 (25.05) | 123 (21.39) | 104 (21.22) | 82 (20.00) | |
| Existing T2D, No. | 755 | 678 | 543 | 614 | 545 | 468 |
| Weight, mean ± SD, kg | 106.14 ± 24.23 | 103.66 ± 23.67 | 103.22 ± 23.69 | 103.57 ± 23.11 | 103.56 ± 23.86 | 103.68 ± 23.81 |
| Time to follow-up, mean ± SD, mo | 2.62 ± 0.49 | 5.57 ± 0.70 | 11.77 ± 1.09 | 17.83 ± 1.11 | 24.01 ±1.16 | |
| Absolute weight change from baseline, mean (95% CI), kg | −3.01 (−3.29 to −2.73) | −3.40 (−3.88 to −2.73) | −3.00 (−3.57 to −2.43) | −2.78 (−3.43 to −2.13) | −2.45 (−3.12 to −1.77) | |
| Percent weight change from baseline, mean (95%CI) | −2.78 (−3.03 to −2.53) | −3.03 (−3.45 to −2.61) | −2.68 (−3.17 to −2.19) | −2.46 (−3.02 to −1.90) | −2.23 (−2.81 to −1.64) | |
| ≥5% weight loss, No. (%) | 144 (21.24) | 147 (27.07) | 166 (27.04) | 154 (28.26) | 118 (25.21) | |
| ≥7% weight loss, No. (%) | 72 (10.62) | 92 (16.94) | 111 (18.08) | 96 (17.61) | 91 (19.44) |
Abbreviations: CI, confidence interval; SD, standard deviation; T2D, type 2 diabetes.