Table 3.

Evaluation of the Methodological Quality of the Studies Collected in this Review Using the Criteria Established by QUADAS‐2 Tool

	Risk of Bias				Concern as to the Applicability
	Patient Selection	Index Test	Reference Standard	Flow and Timing	Patient Selection	Index Test	Reference Standard
Takasae et al. (1992)27	High	High	High	Uncertain	Low	Low	Uncertain
Ziegler et al. (2001)28	High	High	Low	Uncertain	Low	Low	Low
Balcioglu et al. (2007)29	High	High	Low	Low	Low	Low	Low
Khandoker et al. (2009)30	High	Low	Low	Low	Low	Low	Low
Acharya 201131	High	Uncertain	Uncertain	Uncertain	Low	Low	Uncertain
Seyd et al. (2012)32	High	Low	High	Uncertain	Low	Low	Uncertain
Acharya et al. (2013)33	High	Uncertain	Uncertain	Uncertain	Low	Low	Uncertain
Swapna et al. (2013)34	High	Uncertain	Uncertain	Uncertain	Low	Low	Uncertain