Table 3.

Distribution and Age Effect of Individual High‐Risk Risk Genotypes in Study Patient

SNP	Frequency of High‐Risk Genotype(s) (%)		Age Effect*
	White	Nonwhite	White Change (Yrs)	P Value	Nonwhite Change (Yrs)	P
APOE 112R > C 158C > R	32	29	−1.8	0.06	−0.8	0.62
APOB ins, del	9	9	−0.2	0.93	+4.4	0.07
IL6‐174G > C	61	22*	+0.9	0.35	+2.2	0.20
ITGB311T > C	30	18*	−0.6	0.54	+2.7	0.15
ACE ins, del	28	35*	+0.7	0.47	+1.6	0.26
AGTR1 1166A > C	49	21*	+0.7	0.47	+0.6	0.73
CETP 277A > G	84	88	−2.7	0.03	+0.1	0.93
NOS3 894G > T	8	3*	−3.4	0.04	−1.6	0.70
APOA13238C > G	31	30	−0.1	0.90	−1.0	0.52
APOC33238C > G	20	31*	+0.46	0.69	+2.0	0.20
F2 20210G > A	4	2	−0.8	0.74	−2.2	0.66
SELP 76666C > A	82	91*	−0.1	0.91	−1.4	0.57
PON1 584A > G	51	81*	−2.2	0.02	−2.3	0.21
CYBA 242T > C	58	57	−0.8	0.94	+0.9	0.56
F13A1 163T > G	61	61	−0.2	0.87	+0.5	0.74
AGT 235M > T	19	57*	−1.1	0.34	+0.5	0.69
LPL‐93T > G	56	56	−0.1	0.94	+1.1	0.46
PAI1‐675 4G/5G	28	13*	−0.8	0.41	−0.35	0.88

*P < 0.05.

†Age effect was analyzed using multivariate regression modeling. Findings were adjusted for gender, a history of diabetes mellitus, a history of hypertension, and current smoking.