Table 4.

Multivariate Regression Analysis: Factors Associated with a Change in the Age At Onset of a First MI

Variable	White		Nonwhite
	Age Difference (Years)*	P Value	Age Difference (Years)*	P Value
Male	−5.3	<.0001	−2.8	0.09
Hypertension	+4.4	<.0001	+5.3	<.0001
Smoking at any time	−5.2	<.0001	−4.3	0.007
Diabetes mellitus	−0.5	0.09	+0.5	0.15
Change per carried genotype†	−0.6†	0.027	+0.7†	0.16

*Change (increase or decrease) in the number of years at onset of a first MI associated with factor compared to that among patients without the factor.

†Age difference reflects the average change in the number of years at onset of a first MI per carried genotype.

†P value for carriership score × ethnic interaction = 0.02.