Table 2.
Clinical Variables in the Observation Period and the Intervention Period
| Observation Period | Intervention Period | P‐value | |
|---|---|---|---|
| Heart rate at the time of AF recurrence, beats/min | 85 ± 14 | 83 ± 16 | 0.46 |
| Twelve‐lead ECG findings | |||
| Heart rate, beats/min | 64 ± 12 | 62 ± 8 | 0.40 |
| QT interval, ms | 380 ± 46 | 390 ± 59 | 0.05 |
| QTc interval, ms | 391 ± 60 | 397 ± 54 | 0.38 |
| Arterial blood pressure, mmHg | |||
| Systolic | 113 ± 13 | 112 ± 11 | 0.70 |
| Diastolic | 68 ± 7 | 68 ± 6 | 0.76 |
| Echocardiographic findings | |||
| Left ventricular ejection fraction,% | 61 ± 4 | 61 ± 3 | 0.34 |
| Left atrial diameter, mm | 33 ± 4 | 34 ± 4 | 0.54 |
| Blood tests | |||
| LDL cholesterol, mg/dL | 173 ± 35 | 155 ± 32 | <0.001 |
| HDL cholesterol, mg/dL | 58 ± 12 | 59 ± 11 | 0.26 |
| Triglyceride, mg/dL | 188 ± 49 | 161 ± 38 | <0.001 |
| EPA, μg/mL | 42 ± 15 | 120 ± 47 | <0.001 |
| DHA, μg/mL | 77 ± 38 | 80 ± 46 | 0.63 |
| B‐type natriuretic peptide, pg/mL | 37 ± 15 | 39 ± 14 | 0.11 |
| CRP, mg/L | 1.04 ± 0.69 | 0.96 ± 0.56 | 0.24 |
Data represent means ± SD. QTc = rate‐corrected QT interval, LDL = low‐density lipoprotein, HDL = high‐density lipoprotein. EPA = eicosapentaenoic acid, DHA = docosahexaenoic acid, CRP = C‐reactive protein.