Table 3.

Predictors of HF Hospitalization after an AMI

	Univariate Analysis			Multivariate Analysis			Sens./Spec. %	AUC
	HR	95% CI	P	HR	95% CI	P
Age (years)	1.08	(1.05–1.11)	<0.001	1.06	(1.03–1.09)	<0.001
GFR	0.97	(0.96–0.99)	<0.001	0.99	(0.98–1.01)	0.39
Previous AMI	2.81	(1.75–4.51)	<0.001	1.59	(0.88–2.90)	0.13
EF (%)	0.91	(0.89–0.93)	<0.001	0.92	(0.90–0.94)	<0.001
Diabetes	2.95	(1.86–4.68)	<0.001	2.43	(1.51–3.90)	<0.001
BNP (pg/mL)	1.004	(1.003–1.005)	<0.001	1.003	(1.002–1.004)	<0.001		0.77
BNP ≥ 211 pg/mL	7.59	(4.26–13.52)	<0.001	4.75	(2.52–8.96)	<0.001	34/94
SDNN (ms)	0.98	(0.97–0.99)	<0.001	0.99	(0.98–0.996)	0.006		0.69
SDNN ≤ 73 ms	3.06	(1.87–5.03)	<0.001	1.53	(0.91–2.59)	0.11	48/79
α1	0.07	(0.03–0.15)	<0.001	0.15	(0.06–0.38)	<0.001		0.69
α1≤ 1.04	4.29	(2.60–7.08)	<0.001	2.61	(1.53–4.44)	<0.001	44/85
TS (ms/NN)	0.80	(0.73–0.88)	<0.001	0.85	(0.76–0.94)	0.001		0.71
TS ≤ 1.29 ms/NN	3.92	(2.32–6.62)	<0.001	2.53	(1.48–4.32)	0.001	45/83
BRS (ms/mmHg)	0.91	(0.85–0.97)	0.002	0.97	(0.91–1.03)	0.34		0.67
BRS ≤ 3.57 ms/mmHg	2.32	(1.26–4.27)	0.007	1.43	(0.77–2.65)	0.26	40/80
BNP/SDNN	1.30	(1.22–1.38)	<0.001	1.28	(1.19–1.39)	<0.001		0.80
BNP/SDNN ≥ 1.79	7.00	(3.95–12.42)	<0.001	3.93	(2.09–7.41)	<0.001	49/88
Heart rate	1.04	(1.02–1.06)	0.001	1.03	(1.004–1.05)	0.02		0.61
Heart rate ≥ 72	2.50	(1.53–4.10)	<0.001	2.06	(1.25–3.39)	0.005	40/78

α₁= short‐term scaling exponent; AUC = area under the curve in the receiver operator characteristics (ROC) curve analysis; EF = left ventricular ejection fraction; GFR = glomerular filtration rate (mL/min/1.73 m²); HR = hazards ratios obtained from the Cox regression; CI = confidence intervals; Sens./Spec. = sensitivity/specificity. Other abbreviations are same as in Table 2. The cutpoints are optimized from the ROC curves at the sensitivity level from 25% to 50%.