Table 4.
Predictors of Mortality in the Study Population
| Univariate Analysis | Multivariate Analysis | Sens./Spec. % | AUC | |||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |||
| Age (years) | 1.09 | (1.06–1.11) | <0.001 | 1.06 | (1.03–1.09) | <0.001 | ||
| Previous stroke | 4.15 | (2.56–6.74) | <0.001 | 2.94 | (1.79–4.83) | <0.001 | ||
| BNP (pg/mL) | 1.003 | (1.002–1.004) | <0.001 | 1.001 | (1.000–1.002) | 0.17 | 0.65 | |
| BNP ≥ 211 pg/mL | 2.54 | (1.42–4.54) | 0.002 | 1.18 | (0.63–2.19) | 0.60 | 19/92 | |
| SDNN (ms) | 0.99 | (0.98–0.997) | 0.005 | 0.997 | (0.990–1.005) | 0.49 | 0.59 | |
| SDNN ≤ 73 ms | 1.58 | (1.01–2.46) | 0.044 | 1.06 | (0.67–1.66) | 0.82 | 33/77 | |
| α1 | 0.14 | (0.07–0.29) | <0.001 | 0.36 | (0.17–0.78) | 0.009 | 0.67 | |
| α1≤ 1.04 | 2.63 | (1.70–4.06) | <0.001 | 1.46 | (0.92–2.29) | 0.11 | 35/85 | |
| TS (ms/NN) | 0.90 | (0.86–0.96) | <0.001 | 0.97 | (0.91–1.02) | 0.19 | 0.64 | |
| TS ≤ 1.29 ms/NN | 2.18 | (1.37–3.47) | 0.001 | 1.27 | (0.78–2.06) | 0.35 | 34/82 | |
| BRS (ms/mmHg) | 0.96 | (0.92–0.999) | 0.046 | 1.02 | (0.98–1.06) | 0.34 | 0.60 | |
| BRS ≤ 3.57 ms/mmHg | 1.58 | (0.93–2.70) | 0.09 | 0.79 | (0.45–1.39) | 0.41 | 31/80 | |
| BNP/SDNN | 1.18 | (1.10–1.27) | <0.001 | 1.08 | (0.98–1.19) | 0.14 | 0.66 | |
| BNP/SDNN ≥ 1.79 | 2.44 | (1.45–4.10) | 0.001 | 1.33 | (0.76–2.32) | 0.32 | 29/86 | |
| Heart rate | 1.02 | (1.003–1.04) | 0.02 | 1.02 | (1.001–1.04) | 0.04 | 0.56 | |
| Heart rate ≥ 72 | 1.61 | (1.04–2.50) | 0.03 | 1.56 | (0.998–2.42) | 0.051 | 31/83 | |
α1= short‐term scaling exponent; AUC = area under the curve in the receiver operator characteristics (ROC) curve analysis; HR = hazards ratios obtained from the Cox regression; CI = confidence intervals; Sens./Spec. = sensitivity/specificity. Other abbreviations are same as in Table 2.