Table 2.
Comparison of Performance of ECG and Acoustic Cardiographic Parameters to Detect LV Systolic Dysfunction and Elevated LV Filling Pressures, All QRS Durations
For Elevated LV Filling Pressure | ||||||
---|---|---|---|---|---|---|
For EF < 50% | All EF | EF < 50% | ||||
AUC | Sensitivity at 90% Specificity | AUC | Sensitivity at 90% Specificity | AUC | Sensitivity at 90% Specificity | |
QRS duration | 0.82 | 59% (113 ms) | 0.68 | 39% (151 ms) | 0.87 | 67% (114 ms) |
QR interval | 0.80 | 55% (47 ms) | 0.77 | 50% (59 ms) | 0.89 | 74% (46 ms) |
S3 strength | 0.62 | 32% (5.1) | 0.83 | 55% (5.3) | 0.88 | 70% (5.0) |
% EMAT | 0.78 | 43% (12.3) | 0.68 | 32% (14.4) | 0.83 | 56% (12.4) |
EMAT/LVST | 0.80 | 48% (0.33) | 0.72 | 40% (0.36) | 0.85 | 62% (0.33) |
S3 strength* QRS duration | 0.80 | 57% (528) | 0.84 | 50% (672) | 0.97 | 95% (536) |
Cornell voltage | 0.69 | 34% (2363) | 0.58 | 5% (3483) | 0.75 | 55% (2348) |
Cornell product | 0.74 | 41% (245148) | 0.59 | 6% (375212) | 0.79 | 40% (252467) |
Max (P negative area V1, V2) | 0.47 | 6% (6589) | 0.66 | 28% (5726) | 0.62 | 16% (6511) |
ST segment spatial vector magnitude* | 0.77 | 41% (169) | 0.65 | 15% (243) | 0.82 | 52% (171) |
QRSdur* Qrint* S3Strength*%EMAT | 0.88 | 77% (199668) | 0.84 | 55% (466666) | 0.99 | 99% (196558) |
*Spatial vector magnitude is the square root of (STJ20_aVF∧2+STJ20_V2∧2+STJ20_V5∧2).
EMAT = electromechanical activation time; %EMAT = EMAT divided by the R to R interval; LVST = left ventricular systolic time.