Figure 3.

QTcI: Change from baseline (ΔQTcI) across treatment and time points. ∆QTcI after dosing with lomitapide at 75 and 200 mg was overlapping with the placebo‐response. ∆QTcI was mildly prolonged when ketoconazole was given alone or in combination with lomitapide, whereas the prolongation was more pronounced after moxifloxacin. Results from the statistical modeling with the exception of the three early time points for placebo on Day 3 and moxifloxacin, which are based on summary statistics.