Table 2.
Results of 15 Prospective Studies of Microvolt T‐Wave Alternans
| Author | PPV (%) (95% CI) | NPV (%) (95% CI) | RR (95% CI) |
|---|---|---|---|
| Klingenheben et al. 8 | 18 (10−28) | 100 (89−100) | 12.24 (0.75−199.96) |
| Tapanainen et al. 9 | 1 (0−5) | 99 (96−100) | 1.41 (0.09−22.31) |
| Grimm et al. 10 | 16 (11−22) | 90 (81−96) | 1.67 (0.77−3.62) |
| Hohnloser et al. 11 | 16 (9−24) | 94 (80−99) | 2.64 (0.64−10.90) |
| Hohnloser et al. 12 | 13 (7−21) | 100 (90−100) | 9.47 (0.58−155.88) |
| Sarzi Braga et al. 13 | 21 (9−39) | 100 (75−100) | 6.18 (0.38−100.99) |
| Bloomfield et al. 14 | 13 (10−17) | 98 (95−99) | 6.17 (2.26−16.86) |
| Ikeda et al. 15 | 6 (3−9) | 100 (99−100) | 14.59 (4.26−49.99) |
| Baravelli et al. 16 | 23 (11−38) | 93 (78−99) | 3.38 (0.79−14.49) |
| Cantillon et al.*, 17 | 17 (12−23) | 90 (82−95) | 1.68 (0.84−3.37) |
| Chow et al. 18 | 25 (22−29) | 87 (82−91) | 1.89 (1.34−2.67) |
| ALPHA19 | 9 (6−12) | 98 (94−100) | 4.39 (1.35−14.32) |
| MASTER20 | 13 (10−17) | 90 (85−93) | 1.29 (0.80−2.08) |
| SCD−HeFT substudy21 | 17 (13−21) | 88 (81−93) | 1.40 (0.84−2.35) |
| ABCD22 | 8 (6−11) | 96 (91−98) | 1.86 (0.84−4.14) |
| Overall | 14 (13−15) | 95 (94−96) | 2.35 (1.68−3.28) |