Table 1.
QTc Interval and Heart Rate
| QTc (ms) | Heart Rate Median (25–75%) | ||
|---|---|---|---|
| Mean (± SD) | Median (25–75%) | ||
| Ciprofloxacin | |||
| BSL | 409 (10) | 407 (403–417) | 68 (65–79) |
| 2‐hour | 408 (11) | 406 (404–415) | 71 (69–79) |
| 7‐day | 414 (16) | 409 (405–420) | 70 (68–73) |
| Levofloxacin | |||
| BSL | 411 (17) | 408 (401–425) | 71 (65–74) |
| 2‐hour | 404 (8) | 404 (402–405) | 78 (64–83) |
| 7‐day | 409 (10) | 406 (402–416) | 74 (69–78) |
| Moxifloxacin | |||
| BSLa | 409 (12) | 408 (402–414) | 70 (66–74) |
| 2‐hourb | 408 (11) | 403 (401–414) | 69 (65–73) |
| 7‐daya,b | 421 (19) | 414 (410–435) | 76 (70–78) |
aBaseline vs 7‐day (P = 0.022); b2‐hour vs 7‐day (P = 0.003).