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. 2012 Nov 22;18(2):130–139. doi: 10.1111/anec.12005

Table 1.

General Characteristics in the Three Study Groups, Patients with Chronic Heart Failure (CHF) Who Died of Sudden Cardiac Death (SCD) during Follow‐Up, and Survivors Who Had a Left Ventricular Ejection Fraction (LVEF) ≤35% or >35%

SCD Group LVEF ≤ 35% LVEF > 35% P‐Values
N = 12 Group N = 41 Group N = 31
Variables Subjects Subjects Subjects [ANOVA]
Age (years) 67 ± 11 62 ± 12 59 ± 10 NS
M/F 10/2 36/5 29/3 NS
BMI (kg/m2) 25 ± 5 27 ± 4 27 ± 4 NS
HR (beats/min) 72 ± 11 68 ± 9 64 ± 10 NS
SBP (mm Hg) 122 ± 27 114 ± 21 118 ± 22 NS
DBP (mm Hg) 65 ± 14 61 ± 14 64 ± 11 NS
QTend Bazett (ms) 401 ± 75c 390 ± 44 371 ± 30 0.007
QTend Fridericia (ms) 413 ± 73c 382 ± 46 368 ± 33 0.021
QTend Lilly (ms) 416 ± 74c 385 ± 45 369 ± 31 0.013
QTend Framingham (ms) 412 ± 74c 384 ± 45 369 ± 31 0.023
Qpeak Bazett (ms) 305 ± 28 311 ± 42 291 ± 27 NS
QTpeak Fridericia (ms) 300 ± 28 305 ±43 289 ± 28 NS
QTpeak Lilly (ms) 302 ± 28 308 ± 43 290 ± 27 NS
QTpeak Framingham (ms) 302 ± 28 310 ± 41 291 ± 26 NS
Tpeak ‐Tend Bazett (ms) 116 ± 63a,c 78 ± 30 79 ± 17 0.002
Tpeak ‐Tend Fridericia (ms) 113 ± 62a,c 76 ± 30 79 ± 17 0.003
Tpeak ‐Tend Lilly (ms) 114 ± 62a,c 77 ± 30 79 ± 17 0.003
Tpeak‐Tend Framingham (ms) 121 ± 70a,c 89 ± 34 83 ± 23 0.015
Coronary disease
 1 Vessel 2 1 2 NS
 2 Vessels 4 17 14 NS
 3 Vessels 6 23 15 NS
 LVEF (%) 42 ± 8b 30 ± 5d 45 ± 7 0.0001
 NYHA class (I/II/III) 1/8/3 3/19/19 6/19/7 NS
 Serum K+ 4.1 ± 0.1 4.1 ± 0.2 4.2 ± 0.3 NS
 β‐blockers 8 31 24 NS
 Furosemide 4 26 8 NS
 ACEi/Sartans 9 29 30 NS
 Spironolactone 3 16 8 NS
 Digoxin 2 10e 0 0.033
 Amiodarone 2 2 1 NS

Data are expressed as mean ± SD.

P < 0.05 SCD vs LVEF ≤ 35% group. bP < 0.001 SCD vs LVEF ≤ 35% group. cP < 0.05 SCD vs LVEF > 35% group. dP < 0.001 LVEF ≤ 35% vs LVEF > 35% group. eP < 0.05 LVEF ≤ 35% vs LVEF > 35% group.

M/F = male/female; BMI = body mass index; HR = heart rate; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association.