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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Thromb Haemost. 2019 Feb 7;119(5):716–725. doi: 10.1055/s-0039-1678694

Fig. 2. MEF2C deficient cells are defective in candidate target gene expression.

Fig. 2.

Expression of WASF2, MOV10, HDAC1, AGO3, and RBBP5 was measured by qRT-PCR in Meg01 and Meg01-MEF2CKO cells under (A) untreated and (B) PMA-exposed conditions. (C) Fold induction values for target genes in Meg01 and Meg01-MEF2CKO cells treated with PMA. (D) Target gene expression in CHOP10-MEF2CKO iPSC derived megakaryocytes relative to control CHOP10 iPSC derived megakaryocytes. (E) Target gene expression in CB CD34+ derived megakaryocytes transfected with siRNA directed against MEF2C relative to control cells. All qRT-PCR values were normalized to GAPDH expression. P-value above bars. NS=non-significant.