Table 4.
Relation Between Heart Rate Turbulence Analysis, Clinical Characteristics, and Follow‐Up Results in 43 Healthy Volunteers
| HRT Onset ≥0% | HRT Slope ≤ 2.5 ms per RRI | |||
|---|---|---|---|---|
| Yes | No | Yes | No | |
| Number of healthy volunteers | 8 (19%) | 35 (81%) | 2 (5%) | 41 (95%) |
| Age (years) | 49 ± 12 | 51 ± 10 | 58 ± 3 | 48 ± 5 a |
| Men/women | 6/2 | 21/14 | 1/1 | 26/15 |
| Echocardiographic evaluation | ||||
| LV end‐diastolic diameter (mm) | 48 ± 3 | 49 ± 5 | 50 ± 5 | 49 ± 4 |
| LV ejection fraction (%) | 70 ± 6 | 70 ± 4 | 63 ± 4 | 70 ± 4 |
| 24‐Hour Holter electrocardiogram | ||||
| Mean R‐R interval (ms) | 829 ± 96 | 820 ± 106 | 776 ± 93 | 824 ± 104 |
| SDNN (ms) | 148 ± 30 | 142 ± 36 | 118 ± 26 | 144 ± 35 |
| Frequent VPDs (>10/hour) | 1 (12%) | 6 (17%) | 0 (0%) | 7 (17%) |
| Couplets of VPDs | 1 (12%) | 5 (14%) | 0 (0%) | 6 (15%) |
| Nonsustained VT | 0 (0%) | 1 (3%) | 0 (0%) | 1 (2%) |
| Follow‐up results | ||||
| Follow‐up duration (months) | 34 ± 16 | 27 ± 13 | 48 ± 5 | 27 ± 13 |
| All‐cause mortality | 1 (12%)b | 0 (0%) | 1 (50%)b | 0 (0%) |
| Cardiac death | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
RRI = R‐R interval; other abbreviations as in Table 1. aP < 0.05. bDeath due to cancer, which was first diagnosed several months after study enrollment.