| PUMA |
p53 upregulated modulator of apoptosis, BCL2 binding component 3 |
Pro-apoptotic initiators |
| BIM |
BCL-2 interacting mediator of cell death, BCL2 like 11 |
| BID |
BH3 interacting domain death agonist |
| BAD |
BCL2 associated agonist of cell death |
BCL2/MCL1 inhibitors |
| NOXA |
Phorbol-12-myristate-13-acetate-induced protein 1 |
| BAX |
BCL2 associated X, apoptosis regulator |
Apoptosis effectors |
| BAK |
BCL2 antagonist/killer 1 |
| CytC |
Cytochrome c, somatic |
| SMAC |
Diablo IAP-binding mitochondrial protein |
| XIAP |
X-linked inhibitor of apoptosis |
| APAF1 |
Death-associated APAF1-related killer |
| BCL-2 |
B-cell lymphoma-2, apoptosis regulator |
Anti-apoptotic factors |
| BCL-XL |
B-cell lymphoma-extra large, BCL-2 like 1 |
| BCL-W |
B-cell lymphoma-W, BCL-2 like 2 |
| MCL1 |
MCL1 apoptosis regulator, BCL2 family member |
| Caspase-3 |
Cysteine-aspartic acid protease-3 |
Caspase cascade |
| Caspase-7 |
Cysteine-aspartic acid protease-7 |
| Caspase-9 |
Cysteine-aspartic acid protease-9 |
