Table 2.
Sample characteristics from included studies.
| Study | Obstructive sleep apnea | Controls | ||||
|---|---|---|---|---|---|---|
| Number | Age | Gender | Number | Age | Gender | |
| Noda et al., 199814 ╡ | 18 | 55.9 (43 - 76) | 18 ♂ | 10 | 53.2 (45 - 65) | 10 ♂ |
| Wiklund et al., 200017 | 51 | 52 (30 - 75) | 12 ♀, 39 ♂ | 66 | 52 (30 - 76) | 32 ♀, 34 ♂ |
| Aydin et al., 200418┼ | 36 | NA | 36 ♂ | 24 | 43.58 + 7.6 | 24 ♂ |
| Wakai et al., 200416¥ | 36 | NA | NA | 19 | 53.2 + 11.6 | 10 ♀, 9 ♂ |
| Chrysostomakis et al., 200619 ╧ | 31 | 49.2 ± 7.6 | 8 ♀, 18 ♂ | 19 | 51.6 + 9.6 | 8 ♀,11 ♂ |
| Coruzzi et al., 200620 | 10 | 48 ± 10 | 4 ♀, 6 ♂ | 10 | 42 + 8 | 5 ♀, 5 ♂ |
| Aytemir et al., 200721 | 45 | 51 ± 9 | 11 ♀, 34 ♂ | 24 | 50 + 9 | 5 ♀, 19 ♂ |
| Zhu et al., 201222 | 23 | 45 ± 8 | 8 ♀, 15 ♂ | 23 | 45 + 15 | 9 ♀, 14 ♂ |
| Chang et al., 201324 | 13 | 49.8 ± 7 | 13 ♂ | 13 | 46 + 9.4 | 13 ♂ |
| Kim et al., 201523 | 83 | 40.43 ± 9.92 | 83 ♂ | 81 | 38.69 + 10.03 | 81 ♂ |
| Palma et al., 201525╫ | 30 | NA | NA | 20 | 51.2 + 11.8 | 5 ♀, 15 ♂ |
| Xie et al., 201715╤ | 137 | NA | NA | 31 | 48 + 13.24 | 4 ♀, 27 ♂ |
Data are reported as mean + SD (range).
Recruited patients allocated in two groups: severe OSAS (n=10) and mild OSAS (n=8).
Recruited patients allocated in two groups: severe OSAS (n=19; age 44.15 ± 8.3) and mild OSAS (n=17, age 47.17 ± 9.4).
OSA patients divided in two groups: severe OSAS (n=19; age 47.3 ± 13.3, gender 1 ♀, 18 ♂) and mild OSAS (n=17, age 54.8 ± 8.8, gender 2 ♀, 15 ♂).
OSA patients had different severity OSA classification: severe OSA (n=21) and mild OSA (n=5).
Recruited patients allocated in two groups: moderate OSA (n=16; age 51.8 ± 13.4, gender 3 ♀, 13 ♂) and severe OSA (n=14; age 52.3 ± 11.9, gender 3 ♀, 11 ♂).
Recruited patients allocated in two groups: severe OSA (n=82; age 50.6 ± 12.28, gender 14 ♀, 68 ♂) and mild-moderate OSA (n=55; age 50.57 ± 12.02, gender 12 ♀, 43 ♂).
♀, female; ♂, male; NA, not applicable; NR, not reported.