Table 2. Univariate and multivariate analyses of clinicopathological factors influencing overall survival in GC patients.

Risk factors	Univariate analysis			Multivariate analysis
	HR	P value	95% CI	HR	P value	95% CI
SNHG12 expression (low, high)	1.462	0.029*	1.040 - 2.057	1.528	0.015*	1.085 - 2.152
Age (≤ 60, > 60)	1.694	0.008**	1.150 - 2.496	1.871	0.002**	1.263 - 2.769
Tumor invasion depth (T1, T2 + T3 + T4)	8.843	0.030*	1.236 - 63.293
Lymph node metastasis (N0, N1 + N2 + N3)	2.056	0.001**	1.330 - 3.177
Distant metastasis (M0, M1)	2.357	0.007**	1.269 - 4.376	1.980	0.036*	1.046 - 3.748
TNM stage (I + II, III + IV)	2.082	< 0.001**	1.437 - 3.017	1.767	0.004**	1.205 - 2.591
Histological grade (low, middle + high)	0.719	0.075	0.501 - 1.033
Gender (female, male)	1.307	0.157	0.902 - 1.895

HR: hazard ratio, CI: confidence interval; *P < 0.05, **P < 0.01, statistically significant results (in bold)