Table 1. Demographic and clinical characteristics of the training cohort.
Characteristic | Variable | A09≤9%(n=61) | A09>9%(n=649) |
Gender | Female/Male | 4/57 | 141/508 |
Age | years±SD | 54.62±11.02 | 51.69± 11.42 |
stratified AFP | 40–100/100–400/400–1000/1000~ | 21/24/7/9 | 109/172/125/243 |
HBsAg | -/+ | 6/55 | 95/554 |
HBV DNA | 0/3/4/5/6 | 28/12/12/8/1 | 344/124/93/75/13 |
HCV | -/+ | 61/0 | 643/6 |
Ascites | mild/middle/large | 48/13/0 | 573/74/2 |
HLNE | -/+ | 57/4 | 646/3 |
Liver cirrhosis | -/+ | 6/55 | 102/547 |
Tumor number | 1/>1 | 47/14 | 507/142 |
Tumor capsular | imcomplete/complete | 19/42 | 258/391 |
TMD | cm | 4.37±2.84 | 4.89±3.23 |
PBT | -/+ | 59/2 | 630/19 |
Differentiation | poor/moderate/well | 0/46/15 | 13/538/98 |
MVI | -/+ | 42/19 | 446/203 |
AFP | ng/mL ± SD | 1954.49±6558.55 | 3274.63±7588.34 |
AFPDAY | 0.07±0.02 | 0.14±0.06 | |
E50time | day | 11.78±20.47 | 3.92±0.92 |
WBC | 1 × 109/L ± SD | 5.94±2.95 | 5.62±2.62 |
PLT | 1 × 109/L ± SD | 119.79±55.94 | 143.94±60.64 |
PA | g/L± SD | 0.20±0.06 | 0.21±0.05 |
TB | umol /L ± SD | 13.27±5.86 | 12.71±5.28 |
ALB | g/L± SD | 40.38±2.86 | 40.70±3.31 |
ALT | U/L ± SD | 68.89±186.11 | 43.92±77.62 |
GGT | U/L ± SD | 79.62±58.49 | 75.25±73.93 |
ALP | U/L ± SD | 87.85±32.99 | 82.77±33.79 |
CEA | ng/mL ± SD | 2.78±1.59 | 2.56±2.09 |
CA19-9 | U/mL ± SD | 35.80±40.25 | 22.70±22.53 |
Values are presented as n (%) or mean ± standard deviation(SD).
Abbreviation: ALT: alanine transaminase, AFP: alpha fetoprotein, CEA: carcinoembryonic antigen, CA19 -9: carbohydrate antigen 19 -9, HBsAg: hepatitis B surface antigen, HCV: anti-hepatitis C virus, HLNE: Hilar lymph node enlargement, TMD: tumor maximum dimension, MVI: microvascular invasion, AFPDAY: daily decrease of post-operation/preoperative AFP, E50time:half-life of AFP, WBC: white blood cell, PLT: blood platelet, PA: prealbumin, TB: total bilirubin, ALB: albumin, GGT: gamma-glutamyltransferase, ALP: alkaline phosphatase, HBV DNA 0/3/4/5/6:*100/3/4/5/6