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Global 5-methylated (A), and 5-hydroxymethylated cytosine levels (B) in the hippocampus from different mice groups. Representative Western Blot, and quantification for H3K9me2 (C). Values in bar graphs are adjusted to 100% for protein levels of the Wt Control. Values represented are mean ± Standard error of the mean (SEM); (n = 12 (Wt Control n = 4, 5XFAD Control = 4, 5XFAD UNC0642 n = 4)). *p<0.05.
