Table 2. Univariate/Multivariate cox analyses of recurrence-free survival.

Factor	Cox analysis			Multivariate Cox analysis
	b	P	HR(95% CI)	b	P	HR(95% CI)
Gende r(male/female)	-0.009	0.957	0.71-1.384
Age (>65 years/<=65 years)	-0.030	0.854	0.709-1.329
Grade (G3-4/G1-2)	0.101	0.538	0.803-1.524
T stage (T3-4/T1-2)	0.887	0.000	1.735-3.400	0.708	0.484	0.28-14.746
Lymph node stage (N2-3/N0-1)	0.343	0.631	0.348-5.715
Metastasis (M1/M0)	0.909	0.206	0.607-10.150
Pathological stage (III-IV/I-II)	0.865	0.000	1.7-3.3200	0.121	0.904	0.157-8.107
HGSVA score (high/low)	0.554	0.001	1.269-2.387	0.474	0.004	1.168-2.211

HR, Hazard Ratio; CI, confidence interval; HGSVA, hub gene set variation analysis.