Table 1.
MIC and FICI variations of meropenem and meropenem plus pterostilbene against NDM‐carrying isolates
| Strain | MIC (μg·ml−1) | FICI | MIC (μg·ml−1) | FICI | ||
|---|---|---|---|---|---|---|
| Mep | Pt | Mep (+32 μg·ml−1 Pt) | Mep (+64 μg·ml−1 Pt) | |||
| Escherichia coli ATCC‐25922 | 0.032 | >512 | 0.032 | 1.06 | 0.032 | 1.13 |
| E. coli ZC‐YN3 (NDM‐1) | 16 | >512 | 4 | 0.31 | 2 | 0.25 |
| E. coli ZC‐YN5 (NDM‐5) | 32 | >512 | 8 | 0.31 | 4 | 0.25 |
| E. coli ZC‐YN7 (NDM‐9) | 32 | >512 | 8 | 0.31 | 4 | 0.25 |
| Klebsiella pneumoniae QD‐KP2 (NDM‐1) | 16 | >512 | 4 | 0.31 | 2 | 0.25 |
| E. coli D3 (NDM‐1) | 16 | >512 | 4 | 0.31 | 2 | 0.25 |
| E. coli E1 (NDM‐1) | 16 | >512 | 4 | 0.31 | 2 | 0.25 |
| E. coli 2Z49 (NDM‐5) | 16 | >512 | 8 | 0.56 | 4 | 0.38 |
| E. coli 2Z69 (NDM‐5) | 128 | >512 | 64 | 0.56 | 32 | 0.38 |
| E. coli E4 (NDM‐5) | 64 | >512 | 32 | 0.56 | 16 | 0.38 |
| E. coli E2 (NDM‐9) | 64 | >512 | 16 | 0.31 | 8 | 0.25 |
Abbreviations: FICI, fractional inhibitory concentration index; Mep, meropenem; NDM, New Delhi metallo‐β‐lactamase; Pt, pterostilbene.
Note. All data are mean ± SD, n = 5.