. 2019 Nov 8;176(23):4421–4433. doi: 10.1111/bph.14790

Table 1.

Overview of SGs assembly in human cancer cells

Tumour types (human)	Physiological function	References
Pancreatic cancer	Regulated by mutant KRAS gene, promoting survival of cancer cells	Grabocka & Bar‐Sagi, 2016
Hepatocellular carcinoma	Resistance to chemotherapeutic drugs like sorafenib	Adjibade et al., 2015
Glioma/glioblastoma	Assembly in the eIF2A‐dependent way, promoting survival of cancer cells	Vilas‐Boas Fde et al., 2016
Sarcoma	YB1 and G3BP1 participating in related biological pathways, associated with the poor prognosis	Somasekharan et al., 2015
Mantle cell myeloma	Assembly in response to bortezomib while resistant to bortezomib‐induced apoptosis	Fournier et al., 2010
Colorectal cancer	Induced by 5‐fluorouracil (5‐Fu) or bortezomib in the eIF2A‐dependent way, promoting survival of cancer cells	Fournier et al., 2010
Colorectal cancer		Mazroui et al., 2007
Head and neck cancers	Induced by MG132 or 5‐Fu in the eIF2A‐dependent way, promoting survival of cancer cells	Mazroui et al., 2007
Head and neck cancers		Kaehler et al., 2014
Prostate cancer	Induced by the chemotherapeutic drug sodium selenite in the ROS‐dependent way, promoting cell death instead of cell survival	Fujimura, Sasaki, & Anderson, 2012