Table 1. Clinicopathological characteristics of all MBC, ER(+) MBC, and ER(+) MBC with node(+) patients.
| Variables | Total MBC (n = 2,988) | ER(+) MBC (n = 2,581) | ER(+) MBC with node(+) (n = 413) | |
|---|---|---|---|---|
| Age (yr) | ||||
| ≤ 50 | 1,882 (63.0) | 1,615 (62.6) | 270 (65.4) | |
| > 50 | 1,106 (37.0) | 966 (37.4) | 143 (34.6) | |
| Sex | ||||
| Female | 2,965 (99.2) | 2,560 (99.2) | 412 (99.8) | |
| Male | 23 (0.8) | 21 (0.8) | 1 (0.2) | |
| Breast operation | ||||
| BCS | 1,607 (55.3) | 1,455 (56.4) | 149 (36.1) | |
| Mastectomy | 1,368 (44.3) | 1,118 (43.3) | 264 (63.9) | |
| Unknown | 13 (0.4) | 8 (0.3) | 0 (0 ) | |
| Axillary operation | ||||
| SLNB | 1,149 (38.5) | 1,077 (41.7) | 31 (7.5) | |
| ALND | 1,796 (60.1) | 1,473 (57.1) | 382 (92.5) | |
| Unknown | 43 (1.4) | 31 (1.2) | 0 (0) | |
| pT stage | ||||
| T1 | 1,548 (51.8) | 1,354 (52.5) | 129 (31.2) | |
| T2 | 1,258 (42.1) | 1,084 (42.0) | 232 (56.2) | |
| T3 | 153 (5.1) | 120 (4.6) | 46 (11.1) | |
| T4 | 12 (0.4) | 11 (0.4) | 6 (1.5) | |
| Unknown | 17 (0.6) | 12 (0.5) | 0 (0) | |
| pN stage | ||||
| N0 | 2,449 (82.0) | 2,135 (82.7) | 0 (0) | |
| N1 | 381 (12.8) | 328 (12.7) | 328 (79.4) | |
| N2 | 81 (2.7) | 66 (2.6) | 66 (16.0) | |
| N3 | 31 (1.0) | 19 (0.7) | 19 (4.6) | |
| Unknown | 46 (1.5) | 33 (1.3) | 0 (0) | |
| Histologic grade | ||||
| Grade 1 or 2 | 1,740 (58.3) | 1,629 (63.1) | 233 (56.4) | |
| Grade 3 | 231 (7.7) | 196 (7.6) | 71 (17.2) | |
| Unknown | 1,017 (34.0) | 756 (29.3) | 109 (26.4) | |
| LVI | ||||
| No | 1,662 (55.6) | 1,526 (59.1) | 155 (37.5) | |
| Yes | 726 (24.3) | 660 (25.6) | 208 (50.4) | |
| Unknown | 600 (20.1) | 395 (15.3) | 50 (12.1) | |
| ER status | ||||
| Positive | 2,581 (86.4) | - | - | |
| Negative | 233 (7.8) | - | - | |
| Unknown | 174 (5.8) | - | - | |
| PR status | ||||
| Positive | 2,195 (73.5) | 2,136 (82.7) | 317 (76.8) | |
| Negative | 615 (20.5) | 443 (17.2) | 96 (23.2) | |
| Unknown | 178 (6.0) | 2 (0.1) | 0 (0) | |
| HER-2 status | ||||
| Negative | 2,143 (71.7) | 2,025 (78.5) | 280 (67.8) | |
| Equivocal | 235 (7.9) | 220 (8.5) | 53 (12.8) | |
| Positive | 237 (7.9) | 178 (6.9) | 55 (13.3) | |
| Unknown | 373 (12.5) | 158 (6.1) | 25 (6.1) | |
| p53 | ||||
| Negative | 1,572 (52.6) | 1,391 (53.9) | 210 (50.8) | |
| Positive | 669 (22.4) | 604 (23.4) | 116 (28.1) | |
| Unknown | 833 (27.9) | 586 (22.7) | 87 (21.1) | |
| Radiotherapy | ||||
| Yes | 1,500 (50.2) | 1,369 (53.0) | 198 (47.9) | |
| No | 1,078 (36.1) | 925 (35.8) | 159 (38.5) | |
| Unknown | 410 (13.7) | 287 (11.1) | 56 (13.6) | |
| Chemotherapy | ||||
| Yes | 1,416 (47.4) | 1,181 (45.8) | 348 (84.3) | |
| No | 1,252 (42.0) | 1,173 (45.4) | 36 (8.7) | |
| Unknown | 317 (10.6) | 227 (8.8) | 29 (7.0) | |
| Hormone therapy | ||||
| Yes | 2,328 (77.9) | 2,181 (84.5) | 334 (80.8) | |
| No | 258 (8.6) | 116 (4.5) | 23 (5.6) | |
| Unknown | 402 (13.5) | 284 (11.0) | 56 (13.6) | |
| Death | 190 (6.4) | 125 (4.8) | 43 (10.4) | |
| Breast cancer related | 57 (1.9) | 35 (1.4) | 15 (3.6) | |
| Other cause | 133 (4.5) | 90 (3.4) | 28 (6.8) | |
Values are presented as number (%).
MBC = mucinous breast cancer; ER = estrogen receptor; LVI = lymphovascular invasion; BCS = breast conserving surgery; SLNB = sentinel lymph node biopsy; ALND = axillary lymph node dissection; PR = progesterone receptor; HER-2 = human epidermal growth factor receptor 2.