Table 1.
Baseline characteristics of patients with pulmonary TB randomized at 2:1 ratio into V7 and placebo arms.
| Characteristics | V7 N = 100 (%) |
Placebo N = 52 (%) |
P value |
|---|---|---|---|
| Asian | 33 (33%) | 19 (36.5%) | 0.72 |
| Caucasian | 67 (67%) | 33 (63.5%) | |
| Females | 26 (26%) | 7 (13.5%) | 0.1 |
| Males | 74 (74%) | 45 (86.5%) | |
| Age (years) | 39.7±11 | 39.6±10 | 0.96 |
| Height (cm) | 173.1±7 | 172.9±7 | 0.85 |
| Weight (kg) | 64.2±8.3 | 61.5±10.7 | 0.09 |
| BMI (kg/m2) | 21.4±2.1 | 20.5±2.9 | 0.05 |
| AFP-positive smears | 100 (100) | 52 (100) | 1.0 |
| Mean sputum score | 1.23±0.55 | 1.12±0.41 | 0.16 |
| DS-TB | 45 (45%) | 22 (42.3%) | 0.86 |
| MDR-TB | 45 (45%) | 19 (36.5%) | 0.39 |
| XDR-TB | 1 (1%) | 1 (1.9%) | 1.0 |
| TB-HIV | 9 (9%) | 9 (17.3%) | 0.18 |
| DS-TB/HIV | 4 (4%) | 9 (17.3%) | 0.03 |
| MDR-TB/HIV | 5 (5%) | 0 (0%) | 0.17 |
| Leukocytes (x109L) | 8.95±3.7 | 8.1±2.4 | 0.13 |
| Lymphocytes (%) | 26.4±7 | 27.8±5.7 | 0.23 |
| Hemoglobin (g/dL) | 132±17.8 | 128.4±15.8 | 0.22 |
| Total protein (g/L) | 73.8±5.1 | 74.6±6.1 | 0.56 |
| ESR (mm/h) | 18.18±11.9 | 16.88±11.6 | 0.52 |
| ALT (mM/h*L) | 0.34±0.15 | 0.39±0.46 | 0.32 |
| AST (mM/h*L) | 0.16±0.09 | 0.13±0.05 | 0.41 |
| Total bilirubin (µM/L) | 11.4±2.4 | 11.4±2.5 | 0.97 |