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. 2019 Dec 20;10:2910. doi: 10.3389/fmicb.2019.02910

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Copyright © 2019 Chen, Wu, Chen, Li, Li, Zhang, Pang, Wang, Zhao and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bivariate scatterplots showing the Pearson’s correlation of the human fecal S. parasanguinis concentrations determined by metagenomic sequencing, qPCR with primer pair Spa146f-Spa525r, and qPCR with primer pair Spa93f-Spa525r. The correlation coefficient (r), p-value, and the number of fecal samples (n) are shown in each plot. The relative abundances of S. parasanguinis in the metagenomic sequencing dataset were calculated using MetaPhlAn (Segata et al., 2012) in our previous study (Zhang et al., 2015). (A,C,E) The correlation among the data of all 22 tested fecal samples. (B,D,F) The correlation among the data after the removal of one fecal sample containing extraordinarily higher level of S. parasanguinis than other samples.