TABLE 1.
Animal number | Indian/Chinesea | Age at inoculation (year) | Sexb | Virus | Days of infection | Dosage (TCID50 or vRNA copies)c | Routed | Terminal plasma viral load (RNA copies/ml) | Cause of death |
AL78 | CHI | 5.2 | F | SHIV162P3 | 204 | 300 | IVAG | <125 | Euthanasia |
BA69 | IND | 9.6 | F | SHIV162P3 | 175 | 300 | IVAG | <125 | Euthanasia |
BA11 | IND | 10.6 | F | SHIV162P3 | 175 | 300 | IVAG | <125 | Euthanasia |
BN81 | IND | 5.9 | F | SHIV162P3 | 520 | 5000 | IR | <125 | Intestine Torsion |
CR02 | CHI | 6.2 | F | SHIV162P3 | 129 | 300 | IVAG | 699 | Euthanasia |
BN87 | IND | 6.7 | F | SHIV162P3 | 175 | 300 | IVAG | 2425 | Euthanasia |
R870 | IND | 11.3 | F | SHIV162P3 | 175 | 300 | IVAG | 181619 | Euthanasia |
V120 | IND | 9.7 | F | SHIV162P3 | 175 | 300 | IVAG | 916 | Euthanasia |
GE64 | CHI | 5.0 | F | SHIV162P3 | 129 | 500 | IVAG | 1123 | Euthanasia |
DE99 | IND | 4.9 | M | SIVMAC239 | 119 | 100 | IV | 43244100 | Euthanasia due to poor prognosis |
DG96 | IND | 4.7 | M | SIVMAC239 | 147 | 100 | IV | 12411500 | Euthanasia due to poor prognosis |
J541 | CHI | 10.8 | F | SIVMAC239 | 556 | 100 | IV | 2057775 | Colitis |
CR83 | IND | 3.1 | F | SIVMAC239 | 616 | 100 | IV | 5458 | Euthanasia |
DD88 | IND | 2.2 | F | SIVMAC239 | 385 | 100 | IV | 921755 | Euthanasia due to poor prognosis |
CA84 | IND | 4.5 | M | SIVMAC239 | 628 | 100 | IV | 8285600 | AIDS |
DD95 | IND | 2.6 | M | SIVMAC239 | 468 | 100 | IV | 1819200 | Euthanasia due to poor prognosis |
V515 | CHI | 4.2 | F | SIVMAC239 | 668 | 100 | IV | 183648 | Mycobacterium avium intracellulare |
AL26 | CHI | 3.1 | M | SIVMAC239 | 685 | 100 | IV | 949800 | Interstitial Pneumonia |
P772 | CHI | 6.5 | F | SIVMAC239 | 819 | 100 | IV | 2269180 | Pneumocystis carinii infection |
L395 | CHI | 8.9 | F | SIVMAC239 | 1313 | 100 | IV | 667 | Amyloidosis |
V542 | CHI | 4.1 | M | SIVMAC239 | 1845 | 100 | IV | 220 | Pneumonia |
I553 | IND | 12.2 | F | SIVMAC239 | 655 | 100 | IV | 1895400 | Pneumocystis carinii infection |
T798 | IND | 6.3 | M | SIVMAC239 | 962 | 100 | IV | 85463 | Mycobacterium avium intracellulare |
FA97 | CHI | 11.8 | M | SIVMAC239 | 316 | 194,981∗ | IV | 3985200 | AIDS/CMV infection |
BE86 | IND | 5.9 | F | SIVMAC251 | 837 | 100 | IV | 76639 | Mycobacterium avium intracellulare |
DG55 | IND | 3.7 | M | SIVMAC251 | 78 | 100 | IR | 413577 | Euthanasia |
CF35 | IND | 4.2 | M | SIVMAC251 | 93 | 200 | IR | 2183900 | Euthanasia |
DB53 | IND | 4.9 | M | SIVMAC251 | 79 | 200 | IR | 127999 | Euthanasia |
DT83 | CHI | 8.1 | F | SIVMAC251 | 456 | 200 | IR | <125 | Dehydration |
BE64 | IND | 3.3 | F | SIVMAC251 | 752 | 3,300,000∗ | IV | 265116 | Pericarditis |
BE65 | IND | 3.3 | M | SIVMAC251 | 1087 | 3,300,000∗ | IV | 85463 | Mycobacterium avium intracellulare |
CA66 | CHI | 5.7 | M | SIVMAC251 | 746 | 200 | IR | <125 | Generalized amyloidosis |
aIND and CHI denote Indian and Chinese, respectively. bF and M denote female and male respectively. cAll values are expressed as the TCID50, except values denoted by an asterisk (∗), which are vRNA copies. TCID50 and vRNA represent as tissue culture infectivity dose at 50% and viral RNA respectively. dIR, IV, and IVAG denote intrarectal, intravenous, and intravaginal route, respectively. CMV denotes cytomegalovirus.