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. 2019 Nov 16;24(1):451–464. doi: 10.1111/jcmm.14753

Figure 5.

Figure 5

The effect of HOTAIR on the expression of miR‐130a and IGF1 in the ovarian tissues and granulosa cells. Note: A; the expression of miR‐130a in the ovarian tissues of rats in the normal rats and PCOS rat models; B, the mRNA expression of IGF1 in the ovarian tissues of rats in the normal rats and PCOS rat models; C, the protein expression of IGF1 in the ovarian tissues of rats in the normal rats and PCOS rat models; D, the protein band patterns of IGF1 in the ovarian tissues of rats in the normal rats and PCOS rat models; E, the expression of miR‐130a in the ovarian tissues of PCOS rat models; F, the mRNA expression of IGF1 in the ovarian tissues of PCOS rat models; G, the protein expression of IGF1 in the ovarian tissues of PCOS rat models; H, the protein band patterns of IGF1 in the ovarian tissues of PCOS rat models; I, the expression of miR‐130a in the ovarian granulosa cells of PCOS rat models; J, the mRNA expression of IGF1 in the ovarian granulosa cells of PCOS rat models; K, the protein expression of IGF1 in the ovarian granulosa cells of PCOS rat models; L, the protein band patterns of IGF1 in the ovarian granulosa cells of PCOS rat models; **P < .01 compared with the normal group; *P < .05 compared with the control group or blank group; and PCOS, polycystic ovaries syndrome