Figure 1.

Glucose limitation suppresses BAG3 expression in dependent of p53. (A‐B), real‐time RT‐PCR analysis of BAG3 mRNA (A) and immunoblot analysis of BAG3 protein (B) in HCT116 cells with wild‐type p53 (p53+/+) or deletion (p53−/−). (C‐D), real‐time RT‐PCR analysis of BAG3 mRNA (C) and immunoblot analysis of BAG3 protein (D) in MEF p53+/+ and p53−/− cells. E‐F, real‐time RT‐PCR analysis of BAG3 mRNA (E) and immunoblot analysis of BAG3 protein (F) in MCF7 and Bel‐7402 cells. G, Analysis of nascent BAG3 mRNA in HCT116 p53+/+ and p53−/− cells. H, Schematic diagram of the BAG3 gene with two potential p53 responsive element (RE). I, ChIP analysis of p53 recruitment to the indicated DNA