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. 2019 Nov 20;24(1):276–284. doi: 10.1111/jcmm.14717

Figure 2.

Figure 2

Artesunate inhibited HMGCR expression. A, The expression of HMGCR in U87 and U251 cells upon treatment with artesunate was examined. B, A soft agar assay was performed using HMGCR knockdown U87 and U251 cells. C, A soft agar assay was performed using artesunate‐ and/or lovastatin‐treated U87 cells. D, A soft agar assay was performed to examine the rescue effects of FPP. Scale bar, 100 µm. *P < .05; **P < .01