Figure 2.

IM‐1918 inhibits TGF‐β‐induced fibrotic response via Erk1/2 and AKT down‐regulation. CCD18‐Lu cells were treated with the indicated dose of IM‐1918. Two hours later, TGF‐β1 (1 ng/mL) was added, and the cells were incubated for 24 h. Total protein was isolated and analysed by Western blotting for the indicated proteins. A, Smad signalling. B, Non‐Smad signalling. C, FGFR