Table 3.
Univariate and multivariate analysis of the prognostic value of the 2‐gene signature in terms of OS in UPS/MFS
| Parameters | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| p | HR | 95% CI (lower/upper) | p | HR | 95% CI (lower/upper) | |||
| Age (Continuous) | 0.919 | 1.002 | 0.963 | 1.043 | ||||
| Gender | ||||||||
| Male (N = 30) | 1.000 | |||||||
| Female (N = 31) | 0.267 | 0.576 | 0.217 | 1.525 | ||||
| Pathological tumour size (mm) | <0.001 | 1.155 | 1.076 | 1.241 | 0.001 | 1.142 | 1.058 | 1.233 |
| Residual tumour | ||||||||
| Yes (N = 20) | 1.000 | |||||||
| No (N = 39) | 0.916 | 0.944 | 0.323 | 2.761 | ||||
| Radiation treatment adjuvant | ||||||||
| Yes (N = 34) | 1.000 | |||||||
| No (N = 25) | 0.278 | 1.698 | 0.653 | 4.414 | ||||
| Pharmaceutical drug adjuvant | ||||||||
| Yes (N = 10) | 1.000 | |||||||
| No (N = 49) | 0.648 | 0.768 | 0.247 | 2.388 | ||||
| FNCLCC grade | ||||||||
| 1/2 (N = 18) | 1.000 | |||||||
| 3 (N = 43) | 0.362 | 1.786 | 0.513 | 6.219 | ||||
| 2‐gene signature (ITGA10/PPP2R2B) | 0.001 | 1.895 | 1.315 | 2.731 | 0.002 | 2.283 | 1.358 | 3.835 |
Multivariate analysis was conducted by forward: LR method.
Bold value indicates P < .05.