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Glycyrrhizin inhibits HMGB1 synthesis and release. A,B, Plasma level of HMGB1 detected by ELISA at 2 and 12 wk after irradiation. C,D, Relative mRNA expression of HMGB1 in the lung tissue after irradiation. E,G, Western blotting analysis of HMGB1 in the lung tissues at 2 and 12 wk after irradiation. F,H, Relative qualification of HMGB1 content in the lung tissue after irradiation. (*P < .5, **P < .01, ***P < .001)
