Figure 1.

Patient population and timeline of disease activity and venous thromboembolism (VTE). (a) Flow diagram depicting patient screening, enrollment, and follow-up. VTE^neg patients did not experience a VTE during the study, VTE^pos patients did experience a VTE during the study. *One VTE^pos patient had a remote VTE but was included in the VTE^pos group except for time-to-event analyses. **These patients were not screened for enrollment but appropriate samples were available due to the longitudinal nature of our Clinical Core. (b) Diagram depicting timeline of active disease, VTE, and remission dates for VTE^pos patients. Time 0 is the enrollment or active disease date. ○ is the enrollment or active disease sample, Δ is the date of the VTE, and □ is the remission sample. Patients 8 through 12 were added retrospectively. (c) Box and whiskers plot showing the follow-up time for VTE^neg patients (median 24.9 month [m]) and time to VTE for the VTE^pos patients (1.6 m). ANCA, anti-neutrophil cytoplasmic autoantibody; avg, average; neg, negative; pos, positive.