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Pharmacokinetic–Pharmacodynamic Parameter Estimates Obtained After Sequential Modeling
| Parameter | Estimate | RSE % |
|---|---|---|
| CL (L/h) | 0.85 | 5 |
| V1 (L) | 0.56 | 15 |
| V2 (L) | 0.49 | 16 |
| Q2 (L/h) | 0.46 | 24 |
| V3 (L) | 1.26 | 10 |
| Q3 (L/h) | 0.14 | 12 |
| Ke0 (1/h) | 0.03 | 34 |
| E0 | 100 Fixed | — |
| Slope | 19.1 | 9.3 |
| Gamma | 0.23 | 2 |
