Table 2.
Meta-analyses of MET protein over-expression and survival of surgically resected NSCLC.
| N of studies | Model | HR (95% CI) | Log-rank p | Heterogeneity (p, I2) | Conclusion | |
|---|---|---|---|---|---|---|
| C-MET OS | 15 | Random | 1.623 (1.176–2.240) | 0.003 | <0.001, 85.9% | Positive |
| P-MET OS | 3 | Random | 1.710 (0.823–3.533) | 0.15 | 0.006, 80.2% | Negative |
| Asian OS | 12 | Random | 2.115 (1.440–3.108) | <0.001 | <0.001, 83.5% | Positive |
| Non-Asian OS | 4 | Random | 0.901 (0.586–1.387) | 0.637 | 0.002, 80.0% | Negative |
| Japanese OS | 5 | Random | 1.985 (0.970–4.058) | 0.06 | <0.001, 82.1% | Negative |
| Chinese OS | 5 | Random | 2.627 (1.123–6.146) | 0.026 | <0.001, 90.1% | Positive |
| ADCC OS | 5 | Fixed | 2.220 (1.607–3.066) | <0.001 | 0.781, 0% | Positive |
| RM OS | 7 | Random | 1.107 (0.777–1.579) | 0.573 | <0.001, 78.9% | Negative |
| RM (SP44) OS | 5 | Random | 1.031 (0.668–1.590) | 0.892 | 0.001, 78.1% | Negative |
| H-score | 4 | Random | 1.014 (0.822–1.251) | 0.893 | 0.001, 0.893 | Negative |
| RP OS | 5 | Fixed | 2.107 (1.573–2.823) | <0.001 | 0.521, 0% | Positive |
| MVA OS | 10 | Random | 2.004 (1.229–3.268) | 0.005 | <0.001, 88.4% | Positive |
| UVA OS | 5 | Random | 1.051 (0.745–1.484) | 0.776 | 0.010, 69.7% | Negative |
N, Number; HR, Hazard Ratio; CI, Confidence Interval; OS, Overall Survival; ADCC, Adenocarcinoma; RM, Rabbit Monoclonal; RP, Rabbit Polyclonal; MM, Mouse Monoclonal.