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. 2019 Dec 20;9:1450. doi: 10.3389/fonc.2019.01450

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Copyright © 2019 Kong, Li, Liu, Cui, Wang, Zhang, Tang, Du, Liu, Wu and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of SIX1 and EYA1 in PTC tissues. The semi quantitative results displayed as median ± stand error (A). The relative expression of SIX1 and EYA1 in thyroid carcinoma tissue microarray, including normal thyroid tissue, atypical adenoma, oncocytoma, colloid adenoma, fetal adenoma, follicular adenoma, follicular carcinoma, medullary carcinoma, papillary carcinoma, and anaplastic carcinoma, ^*represents a statistical difference was found compared with normal tissue. (B) Representative immunohistochemistry images of SIX1 and EYA1 expression in normal thyroid, papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), medullary thyroid carcinoma (MTC), and anaplastic thyroid cancer (ATC). (C) The positive relationship between SIX1 and EYA1 in thyroid malignant carcinoma.