Table 1.
Association between SIX1/EYA1 expression and clinicopathologic factors in papillary carcinoma (TH8010 + TH802a).
| Characteristics | SIX1 expression | EYA1 expression | ||||
|---|---|---|---|---|---|---|
| Low (≤6) | High (>6) | p | Low (≤6) | High (>6) | p | |
| Sex | 0.481* | 0.177* | ||||
| Male | 4 | 8 | 3 | 9 | ||
| Female | 24 | 30 | 25 | 29 | ||
| Age (y) | 38.96 ± 2.429 | 49.63 ± 2.662 | 0.006† | 39.5 ± 2.434 | 49.24 ± 2.7 | 0.012† |
| Tumor size | 0.347* | 0.145* | ||||
| ≤4 cm (T1 + T2) | 12 | 12 | 13 | 11 | ||
| >4 cm (T3 + T4) | 16 | 26 | 15 | 27 | ||
| Lymph node metastasis | 0.043* | 0.030* | ||||
| Absent | 23 | 23 | 24 | 22 | ||
| Present | 4 | 14 | 4 | 14 | ||
| Stage | 0.015* | 0.015* | ||||
| I + II | 24 | 22 | 24 | 22 | ||
| III + IVA | 4 | 16 | 4 | 16 | ||
*
Person chi-square test.
†
Independent-sample t-test.